Grants for Research from the American German Shepherd Dog Charitable Foundation - American German Shepherd Charitable Foundation

April:

Grant 12CA033 - Evaluating a novel drug for Lymphoma. Dr. Barbara Biller, Colorado State University. $2,000.00.

April:

Grant 1609 - Enteritis - Probiotic VSL#3 Reduces Enteritis in Dogs with Inflammatory Bowel Disease. Albert E Jergens, Iowa State University. $2,500.00.
Grant #1585 - Lymphoma - Phase 1 Study of Involved-Field Radiotherapy (IFRT) for Advanced Stage Canine Lymphoma. Dr. Michael Devereau, DVM, Texas A & M University. $2,500.00.

March:

Grant D09CA-082 - Investigating a Procaspase-3 Activator for the Treatment of Canine Lymphoma – Dr. Laura D. Garrett, University of Illinois $5,000
Grant D08CA-050 – Tyrosine Kinases in Canine Hemangiosarcoma - Dr. Stuart C. Helfand, Oregon State University $10,000

November:

Grant D10CA-051 – Studying Genetic Factors for Inflammatory Bowel Disease in German Shepherds – Dr. Karin A. Allenspach, University of London, United Kingdom $3500
Grant D12CA-302 – Understanding the Role of Specific Cells in Lymphoma Spread, Dr. Daisuke Ito, University of Minnesota, $3500
Grant D09CA-303 – Determining the Best Treatment for Orthopedic Disorders (fragmented coronoid process) – Dr. Ursula Krotscheck, Cornell University $3500
Grant D08CA-504 – Identifying Factors Leading to Early Retirement of Guide and Service Dogs, Dr. James Serpell and Dr. Cynthia M. Otto, University of Pennsylvania, $3500

March:

Grant 01494-A – Comparison of the level of expression of P-glycoprotein in lymph nodes and peripheral blood lymphocytes in canine lymphoma patients – Dr. Bonnie L. Brugman, Louisiana State University $1000
Grant 01503-A – Rational Development of Targeted Therapy-Aurora Kinase Inhibition in Osteosarcoma – Dr. Maime F. Modiano, University of Minnesota $1000
Grant 01418: PET2.0 – Providing Engineered T.-cells (PET): New Genetic and Immunotherapy Targeting Canines with Spontaneous B-cell Lymphoma – Dr. Heather M. Wilson, Texas A & M University $2500
Grant 01429 – Mechanistic Relationship of IL-8 in Cell Proliferation and Survival of Canine Hemangiosarcoma – Dr. Jaime F. Modiano, University of Minnesota $2500
Grant01490-A – Evaluation of Aura kinases inhibitors in canine lymphoma in vitro – Dr. Keijiro Shiomitsu, Louisiana State University $1000

November:

Grant #1557 - High-Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay to Screen for Expression Level Changes - Dr. Matthew Breen, PhD: North Carolina State University $5000
Grant #1609 - Probiotic VSL#3 Reduces Enteritis in Dogs with Inflammatory Bowel Disease -Dr. Albert E. Jergens, DVM, PhD; Iowa State University $2500

April:

Grant 01272 – Isolation and Characterization of Canine induced Pluripotential Stem Cells (iPS) $2500 Grant 00970 – Tissue Regeneration Using Canine Mesenchymal Stem Cells: Effects of Donor characteristics and ex vivo Expansion on Cell Pluripotency - $2500

October:

Grant 01265 - Understanding Mechanisms Involved in Canine Autoimmune and Inflammatory disorders for $2,500.00.
Grant 01271 A&B - Mapping of Additional Genes Associated with Canine Degenerative Myelopathy for $2,500.00.
Grant 1497-A - Dog Leukocyte antigen 88 typing in GSD’s having pancreatic insufficiency for $10,649.00.

The American German Shepherd Dog Charitable Foundation believes the key to improving the diseases of the German Shepherd Dog lie in medical and genetic research. Here are the grants that have been awarded to date. Including the AKC Charitable Health Foundation funds, the AGSDCF, to date, has funded almost $200,000 in research grants for the health of our breed.

Date	Amount	Disease/Condition	University/Organization	Researcher
7/1/2010- 03/31/2011		AKC Canine Health Foundation Active Grant 1497-A Dog leukocyte antigen 88 typing in German Shepherd Dogs having pancreatic insufficiency	Clemson University	Dr. Leigh Anne Clark, PhD
10/2009 -11/2011 Results		Morris Animal Foundation Grant D08CA-500 Epidemiological and Molecular Patterns of Leptospirosis in Dogs in the U.S	Purdue University	Dr. George E. Moore, DVM, PhD
11/09/2009 - 10/31/2010		AKC Canine Health Foundation Active Grant 1364-A Heat shock protein 72 (HSP72) as a biomarker for acclimation to, and performance in high level physical activity in pure-bred military working dogs	Hebrew University of Jerusalem	Dr. Yaron Bruchim, DVM
1/1/2009 - 6/30/2010		AKC Canine Health Foundation Active Grant #1212-A Phenotypic Characterization of Peripheral Nerve Disease in Degenerative Myelopathy Dogs	University of Missouri - Columbia	Dr. Joan Coates, DVM
1/1/2009- 12/31/2009		Active Grant 1147 Identifying Mutations in Genes Associated with Canine Hemangiosarcoma	Tufts University	Dr. Cheiko Azuma, DVM, PhD
1/1/2009- 12/31/2009		Active Grant #1213-A Determination of Outcome Measures for Clinical Progression and Morphometric Studies of Spinal Cord Disease in Degenerative Myelopathy Dogs	University of Missouri - Columbia	Dr. Joan Coates, DVM
10/2008 - 9/2011 Results		Morris Animal Foundation Grant D08CA-050 Tyrosine Kinases in Canine Hemangiosarcoma	Oregon State University	Dr. Stuart C. Helfand, DVM
10/1/2007- 9/30/2009		AKC Canine Health Foundation Closed Grant 760 Cellular Genomics - Molecular Cytogenetic Investigation of Canine Soft Tissue Sarcomas	North Carolina State University	Dr. Matthew Breen, PhD
5/8/2008	$30,000	AKC Canine Health Foundation Pending Grant No. 934 Investigation of Inherited Disease of the German Shepherd Dog Using the SNp>Array	Texas A/M University	Dr. Leigh Anne Clark
5/8/2008	$6,480	AKC Canine Health Foundation Grant No. 1012-A Genetic Studies in Chronic Superficial Keratitis in German Shepherd Dogs	National University of La Plata	Dr. Guillemo Giovambattista
5/7/2008	$3,000	Morris Animal Foundation Grant No. D06CA-065 Reciprocal Relationship of PTEN and p21 in Canine Cancer	University of Minnesota	Dr. Jaime Modiano
5/7/2008	$3,000	Morris Animal Foundation Grant No. D07CA-067 Canine Mammary Tumors Expressing Prolactin Result in Poor Clinical Outcomes	Oregon State University	Dr. Michelle Kutzler
4/3/2008	$6,480	AKC Canine Health Foundation Grant No. 870-A Analysis of Pancreatic Acinar Atrophy in the German Shepherd Dog Using the SNP Array	Texas A/M University	Dr. Leigh Anne Clark
**12/31/2007 Results	$1,876.77	Degenerative Myelopathy Research Contribution made to the AGSDCF that was specifically earmarked for Clemmons' research	University of Florida	Dr. Roger Clemmons
12/01/2006- 12/31/2008		AKC Canine Health Foundation Closed grant 871-A Disease(s): Gastrointestinal: Anal Furunculosis (Perianal Fistula)	University of Manchester	Dr. Lorna J. Kennedy, PhD
12/31/2006 Results	$22,881	Degenerative Myelopathy Research Contribution made to the AGSDCF that was specifically earmarked for Clemmons' research and AGSDCF Matching Funds contributions	University of Florida	Dr. Roger Clemmons
12/31/2005 10/12/05 Results	$11,901.24 $6,901.24	Degenerative Myelopathy Research Contribution made to the AGSDCF that was specifically earmarked for Clemmons' research and AGSDCF Matching Funds contributions	University of Florida	Dr. Roger Clemmons
4/8/2005 Results	$19,150	Degenerative Myelopathy Research Contribution made to the AGSDCF that were specifically earmarked for Clemmons’ research & AGSDCF Matching Funds contributions	University of Florida	Dr. Roger Clemmons
4/8/2005	$2,000	AKC Canine Health Foundation Grant #0257: Investigation of Predicators of Outcome for Canine Mast Cell Tumors	Auburn University	Dr. Elizabeth Whitney
4/8/2005 Results	$5,000	AKC Canine Health Foundation Grant #0276: To Study Microarray Analysis for Cardiac Gene Expression in German Shepherds with Sudden Death	Cornell University	Dr. Sydney Moise
12/13/2004 Results	$7,040	Degenerative Myelopathy Research AGSDCF Matching Funds contributions	University of Florida	Dr.Roger Clemmons
12/13/2004	$2,400	AKC Canine Health Foundation Grant #0305: Study of Autoimmune Diseases	University of Utah	Dr. Wayne Potts
12/13/2004	$11,340	AKC Canine Health Foundation Grant #0454: Pancreatic Acinar Atrophy in th GSD	Texas A&M University	Dr.Keith Murphy
6/30/2004	$15,000	AKC Canine Health Foundation Grant #0276: To Study Microarray Analysis for Cardiac Gene Expression in German Shepherds with Sudden Death	Cornell University	Dr. Sydney Moise
6/30/2004	$3,000	AKC Canine Health Foundation Grant #2629: To Study Clinical and Immunological Outcomes in Dogs with Osteosarcoma Treated with Intratumoral Interleukin-12 Microspheres	University of Wisconsin	Dr.Stuart Helfand
4/18/2004	$15,000	Degenerative Myelopathy Research In addition to the initial donation, the AGSDCF will also match dollar for dollar, up to an additional $10,000 any contribution made to the AGSDCF that are specifically earmarked for Clemmons’ research. Checks must be sent to the Foundation Treasurer.	University of Florida	Dr.Roger Clemmons
6/10/2003	$3,000	AKC Canine Health Foundation Grant #2629: To Study Clinical and Immunological Outcomes in Dogs with Osteosarcoma Treated with Intratumoral Interleukin-12 Microspheres	University of Wisconsin	Dr.Stuart Helfand
1/1/2002- 12/31/2004		AKC Canine Health Foundation Closed Grant 2277 Identification of the Genetic Cause or Causes for Cataracts in Several Breeds	University of Michigan	Dr. George Brewer, MD
10/16/2002	$2,000	AKC Canine Health Foundation Grant #2434: To improve the test used in thyroid conditions	University of Georgia	Dr. Duncan Ferguson (Total AKC CHF grant is $97,878)
10/1/1998	$1,000	AKC Canine Health Foundation Grant #1628: The Genetics of Hypertrophic Osteodystrophy (HOD)	University of California	Davis John Angles, BVSc (An additional $9,000 was added to this study by the AKC CHF and the Weimaraner Club)
6/6/1997	$10,000	AKC Canine Health Foundation, Grant #1632: Canine Degenerative Myelopathy: Role of Methionine Supplementation and Further Evaluation of Associated Enteropathy	Texas A&M University	Joan R. Coates, DVM, MS, DACVIM-Neurology; (An additional $10,000 was added to this study by the AKC CHF)
4/23/1997	$1,000	Fertility Studies on older & valuable breeding stock	Washington State	Shirley Diane Johnston, Assoc. Professor Small Animal Medicine College, Hormone Laboratory
3/17/1997	$12,000	Degenerative Myelopathy Research	Texas A&M University	Dr. David A. Williams, Department of Veterinary Clinical Sciences.
12/28/1994	$7,000	Canine Small Intestine & Pancreatic Diseases	Purdue University	Dr. David A. Williams, Department of Veterinary Clinical Sciences
2/16/1992	$5,000	Degenerative Myelopathy Research Fund	Morris Animal Foundation	Dr. Carole Williams
8/7/1991	$5,000	Degenerative Myelopathy Research Fund	Morris Animal Foundation	Dr. Carole Williams
10/8/1990	$5,000	Degenerative Myelopathy Research Fund	Morris Animal Foundation	Dr. Carole Williams
3/22/1990	$500	Dysplasia Control	University of Missouri Orthopedic Foundation for Animals	Dr. E. A. Corley, Director
3/22/1990	$500	Mycoplasma & Ureaplasma	University of Minnesota	Shirley Diane Johnston, Assoc. Professor of Small Animal Medicine College, Hormone Laboratory, St. Paul, MN.
3/22/1990	$500	Gastric Torsion & Degenerative Myelopathy	University of Pennsylvania	Dr. Edwin J. Andrews, VMD, PHD
3/22/1990	$500	Gastric Torsion & Degenerative Myelopathy	University of Wisconsin Veterinary School	Director of Small Animal Medicine
8/15/1989	$200	Gastric Torsion & Degenerative Myelopathy	University of Pennsylvania, School of Veterinary Medicine	Director of Small Animal Medicine
8/15/1989	$200	Dysplasia Control	University of Missouri Orthopedic Foundation for Animals	Dr. E. A. Corley, Director
8/15/1989	$200	Mycoplasma & Ureaplasma	University of Minnesota	Shirley Diane Johnston, Assoc. Professor of Small Animal Medicine College, Hormone Laboratory, St. Paul, MN
8/15/1989	$200	Mycoplasma & Ureaplasma	Cornell University	Dr. L.E. Carmichael, Director
** Grants, January to December 2007 The Foundation donates funds during the year to the AKC Canine Health Foundation and the Morris Animal Foundation. A number of sponsorships and grant support are not shown during this period as requests from the above-named foundations did not reach the AGSDCF until too late in the year to address them. Early 2008 grant support will appear in the 2008 record. * Large Grant made November 2001 At the November, 2001 AGSDCF Board meeting, the Officers & Directors approved a $50,000 grant as long as the AKC Canine Health Foundation made a matching grant of $50,000 for a total of $100,000. The $100,000 will be used for research that will benefit the German Shepherd Dog. The AKC Canine Health Foundation has agreed to the match and the funds have been forwarded to them. Noted researchers are submitting proposals to the AKC Canine Health Foundation. Both organizations have to agree on the proposal that will be funded. As of May 31, 2005, the AKC Canine Health Foundation Donor Advised Fund has a balance of $41,282 that has yet to be allocated for canine health research.

AGSDCF Purpose

agsdcf_logo_small The American German Shepherd Dog Charitable Foundation, Inc. is a non-profit organization devoted to funding research projects that improve the health of the German Shepherd Dog.

We are grateful to the special dogs who have given their hearts and souls to make our daily lives happier. They ask nothing more than to be loved, fed, and their health needs met.

Your donations to this Foundation will help make future generations healthier and happier.