All dog breeds are susceptible to mammary cancer. Researchers will evaluate the role of citrullination, a cellular process that is mediated by peptidylarginine deiminases (PAD) enzymes, in canine mammary cancer.

PAD activity is usually low in healthy tissues, but it often increases during disease progression, including during breast cancer development. The investigators will study the process of PAD-mediated citrullination in more detail in canine mammary cancer stem cells.

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agsdcf_logo_smallThe American German Shepherd Dog Charitable Foundation, Inc. is a non-profit organization devoted to funding research projects that improve the health of the German Shepherd Dog.

We are grateful to the special dogs who have given their hearts and souls to make our daily lives happier. They ask nothing more than to be loved, fed, and their health needs met.

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