Principal Investigator: Erin B Dickerson, PhD, University of Minnesota
Total Study Cost: $172,431; Grant period: 10/1/2016 – 9/30/2018

Project Abstract:
Hemangiosarcoma is an aggressive and almost uniformly fatal cancer of dogs. Researchers uncovered evidence that a common cellular signaling pathway is associated with aggressive hemangiosarcoma tumor growth and chemotherapy resistance. Signaling pathways are coordinated chemical activities in a cell that collectively control one or more cell functions. Abnormal activation of signals often trigger or facilitate the development of diseases, including cancer. Researchers will investigate how signaling pathways contribute to hemangiosarcoma growth, and if existing drugs can interrupt the process to reduce tumor growth and chemotherapy resistance. Finding a new approach to treat canine hemangiosarcoma is a vital step in improving survival rates in dogs with this aggressive cancer.

AGSDCF Purpose

agsdcf_logo_smallThe American German Shepherd Dog Charitable Foundation, Inc. is a non-profit organization devoted to funding research projects that improve the health of the German Shepherd Dog.

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